Is there enough time in the day to do everything?
Perhaps multitasking you spend your days and trying to beat the clock while working on short list of things to do. Maybe you do not go your days as planned and your to-do list grows consistently at a faster rate than you can keep up with. You are wondering if it is a better way to become more productive, rather than having your morning cup of coffee with a triple shot of espresso of charging.
What are Nootropics?
Nootropics can be the answer you are looking for. The nickname as “smart drugs” or “cognitive enhancer,” these supplements have become increasingly popular in recent years. Nootropics are dietary supplements made from natural or artificial ingredients that help support certain brain functions, including memory, mental speed and focus.
The first nootropic drug, Piracetam, was first synthesized in 1964 by a Romanian psychologist and chemist in Belgium called Corneliu E Giurgea. He was the scientific advisor and researcher at a Belgian pharmaceutical company called UCB. He created Piracetam by chance while he was actually trying to develop a drug to create calming effects and induce sleep. At the time there was a great interest in GABA in pharmacology, such as GABA supplements found to improve mood, anxiety and sleep.
Giurgea created a derivative of GABA in one of his experiments that Piracetam later made.
This derivative seemed to achieve the opposite of the calming and sleep-inducing effects he had originally hoped for, and it led him to coining the term “nootropic” drugs in 1972.
Depending on how Piracetam worked, Giurgea wrote a certain set of properties down which require a drug to fit into this nootropic category.
Nootropics should improve learning and memory, improve the brain’s resistance to conditions, try to disrupt learned behaviors and memories, and protect the brain against various physical or chemical injuries.
They should help the different sections of the brain work together to work more efficiently and improve leadership processing, which includes things like planning, focus and concentration, and spatial perception. After all, the drugs must be unique and different from other psychotropic drugs and must have extremely low side-effect and low toxicity.
Currently, many supplements are classified as nootropics, many of which should not be classified as nootropics, according to Giurgea original criteria. While they all have their differences, they share one thing in common: They help your brain to create more neuronal connections, which in turn increases memory, energy, concentration and focus.
Everything our body does is the result of neurons communicating with each other via electrical impulses and chemical signals.
These signals carry messages between different parts of the brain and the rest of your entire nervous system.
What are Neurotransmitters?
Neurotransmitters are the chemical substances that send chemical messages between neurons. This communication occurs in the synapses or spaces between the neurons. Neurotransmitters are released by a neuron and accepted by the next neurons via a receptor on the membrane. The receptors are specific for the neurotransmitters in shape and size so that they fit together like a key lock. The receptor acts as the lock and the neurotransmitter enters and unlocks it like the button. receptors are the connections where neurotransmitters can carry out their commands. Neurotransmitters are responsible for our thoughts, actions and everything we do.
Some examples of neurotransmitters include serotonin, dopamine, glutamate, GABA and acetylcholine. The list goes on and on from the numerous functions that these keys affect neurotransmitters in our bodies. A brief overview of some of their most important functions show how crucial they are in our body to maintain balance:
- Serotonin helps to control many different functions such as mood, relaxation, appetite and sleep.
- Dopamine helps control movement and helps to promote energy, joy, enjoyment, excitement and motivation.
- Glutamate improves the electrical flow between brain cells and helps with learning and memory.
- GABA helps to provide a feeling of tranquility and stability and helps in the production of endorphins that are our body’s natural “feel-good” chemicals.
- Acetylcholine helps the brain to modulate by changing brain speed. It affects the way the brain processes information because it lubricates the cells so information that can easily pass between the neurons. For this reason acetylcholine increases learning, memory, focus, sensory perception, concentration, recall, excitement, attention, motivation, and general cognitive functions.
- Acetylcholine, glutamate and dopamine all play a significant role in the cognitive function, so nootropic substances that often take over and increase their effect.
Improvements in learning and memory can help fight various types of brain degeneration. By changing the concentration of neurotransmitters in the brain, brain that originally had cognitive deficits in learning and memory can benefit much.
Dietary supplements and medications can either increase or decrease the amount of neurotransmitters in the brain directly or indirectly, they can mimic the neurotransmitter effects, or they can amplify the signals of receptors.
How Do Nootropics work?
The original nootropic, Piracetam, works by amplifying the signals of acetylcholine neurotransmitter receptors in the brain, thereby increasing the effect of acetylcholine. Let us contrast this with the way that the benzodiazepine category of drugs work, including Xanax. Benzodiazepines amplifies the signals of GABA receptors in the brain that cause hypnotic, calming and sedative effects. For this reason, Xanax tends to make people feel tired, relaxed and comfortable, while Piracetam tends to increase people’s learning, memory, concentration and sensory perception.
The entire physiological system that adds with creating, transferring, and receiving the neurotransmitter acetylcholine in the brain is called the cholinergic system. Cholinergic drugs and dietary supplements influence the cholinergic systems in the brain. They can improve, inhibit or mimic the neurotransmitter acetylcholine. Damage to the cholinergic system in the brain’s brain can lead to degeneration, which is why a lack of acetylcholine levels can lead to brain degeneration, such as Alzheimer’s disease or dementia.
Choline is a nutrient found in the foods we eat, like eggs. Our body make acetylcholine from choline, so it is important that we have enough choline in our body. If people have a choline deficiency diet, a cholinergic supplement or medication can give them the extra choline to boost their brains need. Cholinergic drugs choline to the brain supplies so the brain it can produce more acetylcholine. Many nootropics are stacked cholinergic drugs with other substances, such as racetams. Racetam’s work of glutamate receptors are activated, which in turn closeby cholinergic receptors activated. This improves the functions of acetylcholine in the brain and ultimately improves memory. The combination of cholinergic drugs and racetams in nootropic supplements and drugs are typically formulated stacked memory, focus to improve and learning ability.
On the other hand, there are a number of drugs that are classified as anticholinergic and anti-spasmodic drugs. These drugs inhibit the effect of acetylcholine and may increase the risk of dementia in older adults. If you are concerned about this, it is a good idea to investigate whether all your medicines fall into this category.
Natural Nootropic Supplement
A popular and natural nootropic supplement called Alpha BRAIN is currently on the market. Alpha brain uses soil grown and natural ingredients such as Bacopa Minniera, Cat’s Claw, Huperzia Serrata, Oat Straw, L-Tyrosine, L-Theanine, Phosphatidylserine, Pterostilbene and Vitamin B6 memory, to increase mental speed, and focus.
Since L-Tyrosine is an amino acid precursor of dopamine, it can help to increase the production of the neurotransmitter dopamine in our brain. Many users prefer Alpha BRAIN over coffee because it helps them be more productive and efficient without taxing the adrenal system like coffee does. Users also report that it improves their mental performance, helps them to form thoughts and sentences, helps them remember information more easily, improves their concentration and helps them stay in the “zone” of their peak performance.
Unlike the typical prescription drugs nootropics, Alpha BRAIN is BSCG Certified Drug-Free, which means the supplement and its ingredients are free of drugs and other harmful substances that could cause health problems or positive drug test results.
There are many prescription nootropics on the market as well as, like Modanifil, which is a drug to promote alertness. Modanifil is an alertness promoting agent typically used for the treatment of sleep disorders, including excessive drowsiness of narcolepsy, obstructive sleep apnea / hypopnea syndrome and sleep disorders work postpone. It helps to stimulate against insomnia through neuronal activity.
There are different theories about how Modanifil works. It does not cause all the same typical side effects of other central nervous system stimulants, but it is believed to be a central nervous system stimulant. It affects receptors that increase levels of norepinephrine, dopamine and histamine. Research shows that Modanifil influences the neurotransmitters by working on the pathways of glutamate, norepinephrine, adrenaline, histamine and dopamine in the brain. The increase in these neurotransmitters and natural substances present in certain areas of the brain that control sleep and wakefulness causes the overall alertness effect of this drug.
The Bottom Line
As you can see, neurotransmitters have the power only to affect our mood, energy levels, focus, concentration, memory and sleep, but they also have the ability to affect our health positively or negatively both the short and long term. Incorrect balance and deficiencies in each of these neurotransmitters can lead to serious health problems.
For example, deficiencies in acetylcholine can lead to Alzheimer’s disease, dementia, attention deficit disorder and learning disorders, deficiencies in dopamine can lead to Parkinson’s disease, and deficiencies in dopamine and/or serotonin can lead to depression and anxiety.
Trying to change neurotransmitter pathways in your brain to achieve a certain effect is not a decision that can be taken lightly. You can, by changing the delicate and complicated balance of chemicals your brain, for yourself to lead to serious health problems all along the line, so it is a good idea to talk to your doctor about any nootropic supplements or drugs before you start experimenting with them.
Remember that all pills have their own side effects. With so many available nootropic products available, each of which have the potential to help and / or harm your health, your doctor may be able to help you find out best for you. The effects of nootropics differ in everyone because we each have a distinct neurochemistry that affects the nootropics.
Many people enjoy an additional advantage with increased brain functions including memory, learning and concentration as a result of using nootropics. Finding the right nootropic for you can be the next experience you can get to a “borderless” medication.